Primitive Neuroectodermal Tumor of Bone as a Second Malignant Neoplasm in a Child Previously Treated for Acute Lymphoblastic Leukemia

PurposeAlthough rare, second malignant neoplasms (SMNs) are a devastating consequence of successful treatment of childhood cancer. The 15-year estimated risk of developing a second malignant neoplasm after treatment of childhood acute lymphoblastic leukemia (ALL) is 2.5%. Most of these neoplasms are