“Tandem” reactivity of 2-cyano-Δ3-piperideines: a new approach to the synthesis of ervatamine type indole alkaloids.

Abstract Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-Barcelona, Spain. The synthesis of 20-dethylsilicine in four steps, from a 2-cyano-Δ 3 -piperideine substituted at C-3 by a CH 2 OAc group, is reported.