Assessment of the abuse liability of ABT-288, a novel histamine H3 receptor antagonist
2013
Rationale
Histamine H3 receptor antagonists, such as ABT-288, have been shown to possess cognitive-enhancing and wakefulness-promoting effects. On the surface, this might suggest that H3 antagonists possess psychomotor stimulant-like effects and, as such, may have the potential for abuse.
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