Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.

Chesnais,Arcangeli Ml,Delette C,Alice Rousseau,Hélène Guermouche,Lefevre C,S Bondu,Diop M,Meyling Cheok,Nicolas Chapuis,Laurence Legros,Sophie Raynaud,Lise Willems,Didier Bouscary,Evelyne Lauret,O. Bernard,Olivier Kosmider,Françoise Pflumio,M. Fontenay

Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.

2017

Chesnais
Arcangeli Ml
Delette C
Alice Rousseau
Hélène Guermouche
Lefevre C
S Bondu
Diop M
Meyling Cheok
Nicolas Chapuis
Laurence Legros
Sophie Raynaud
Lise Willems
Didier Bouscary
Evelyne Lauret
O. Bernard
Olivier Kosmider
Françoise Pflumio
M. Fontenay

Myelodysplastic syndromes (MDSs) are hematopoietic stem cell disorders in which recurrent mutations define clonal hematopoiesis. The origin of the phenotypic diversity of non-del(5q) MDS remains unclear. Here, we investigated the clonal architecture of the CD34+CD38− hematopoietic stem/progenitor

Keywords:

Progenitor cell
Cancer research
CD34
Immunology
Architecture
Hematopoietic stem cell
Haematopoiesis
Genetics
Myelodysplastic syndromes
Medicine
clonal architecture
Progenitor
Phenotype

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