THE TOXICOLOGY OF DM

Abstract : This report summarizes the toxicological testing of diphenylaminochloroarsine (DM) in animals during the period from 1918 to 1965. Included are determinations of the toxicity of the compound disseminated by laboratory methods in early work and from military and commercially available thermal munitions in later work. The most probable human LCt50 estimates are derived from these experiments for the various methods of dissemination. All work described under the animal-testing section of the report pertains to either field or chamber total body exposures of eight species of test animals. Other portions of the toxicity studies deal with the pathological changes in exposed animals. All available information on human exposure to DM, including accidental exposure of US and alien troops and Army personnel, is included.