Clinical analysis of Acute renal failure in patients with malignant tumors

Objective To analysis the cause and means of therapy and prevention of acute renal failure(ARF) in patients with malignant tumors.Methods Clinical data of 15 patients with malignant tumors experienced ARF were retrospectively studied.Results 11 patients suffered ARF because of hepatorenal syndrome.One patients with multiple myeloma had ARF due to cast nephropathy caused by light chain of Bence-Jones protein.One patients with lung cancer experienced ARF induced by contrast media.ARF in 2 patients resulted from obstruction located downstream of the kidneys.ARF in 1 patient with stomach cancer caused by hypovolemia resultingfrom various causes.Conclusions ARF resulting from various causes is a severe complication with high mortality in advanced tumors.The therapy based on cause is crucial to treat ARF.Maintaining adequate circulating volume in patients of high risk factors,early diagnosis and early treatment may reduce mortality caused by ARF.