Иммунокоррекция бактериальных осложнений у новорожденных детей с дыхательными расстройствами

Respiratory distress syndrome (RDS) is a major cause of morbidity of newborns of high-risk in early neonatal period and largely determines the rate of infant mortality. The purpose of this research was the assessment of the NG system functioning character and the possibility of immunotherapy of their defects using Likopid based on clinical and immunological analysis of infants with RDS who are on artificial lung ventilation. It was found that infants with RDS on ALV, have significant changes in the functional activity of neutrophilic granulocytes, depending on gestational age and duration of ALV. Functional intubation of NG in the phase of reconvalescence of infants with RDS allowed to reveal a tendency to restoration of the studied parameters, more significant in the group of full-term infants. Preventive use of Likopid for infants with RDS since 2-3 days of life allows to eliminate defects of NG functioning in all clinical groups, and significantly reduce the frequency of pyoinflammatory complications progression (average 30%), improve the quality of care and reduce the risk of chronization process.