A Solvent-Free Reaction for Silyl Enol Ethers Synthesis
2018
Silyl enol ethers are extremely useful nucleophilic intermediates for chemical transformations because they are synthetically versatile substrates for a wide range of C–C bond-forming reactions. Here, we present a new, mild, and solvent-free procedure for the synthesis of silyl enol ethers that employs a catalytic amount of solid-supported base and an equimolar amount of N , O -(bistrimethylsilyl)acetamide as a silylating agent.
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