Discovering Drugs through Biological Transformation: Role of Pharmacologically Active Metabolites in Drug Discovery

Bristol Myers Squibb, Pharmaceutical Research Institute, P.O. Box 5400, Princeton, New Jersey 08534, Bristol-Myers Squibb, Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, Connecticut 06492, Bristol Myers Squibb, Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543, and Bristol-Myers Squibb, Pharmaceutical Research Institute, One Squibb Drive, New Brunswick, New Jersey 08903