Bismuth Subnitrate in Comparison to Ranitidine in Patients with Non-ulcer Dyspepsia: A Randomized Controlled Trial

The prevalence of dyspeptic disorders is high and has not changed within the last 40 years [13]. The term non-ulcer dyspepsia (NUD) describes a complex of symptoms, e.g., postprandial feeling of fullness, burping, flatulence, heart burn, nausea, epigastric pain, and lack of appetite [21]. NUD is very heterogenous and hard to define; [5, 32] it has great socioeconomic impact because the average notification of sickness is 26 days annually for NUD patients [19].