Esterification reaction-pervaporation membrane separation integrated method for producing methyl 3-hydroxypropionate
2012
The invention relates to an esterification reaction-pervaporation membrane separation integrated method for producing methyl 3-hydroxypropionate. The method comprises a process of performing esterification reaction between methanol and 3-hydroxypropionic acid to generate methyl 3-hydroxypropionate, wherein the process comprises the following steps: (1) mixing 3-hydroxypropionic acid and methanol in an esterification reactor, heating, then adding a catalyst, and reacting; and (2) pumping the obtained reaction solution into a pervaporation membrane separation device, dewatering the reaction liquid through the membrane, circularly returning the reaction solution into the esterification reactor, and further performing esterification reaction, thus obtaining the high-purity methyl 3-hydroxypropionate product after the esterification reaction is completed. According to the method provided by the invention, the area of the used membrane is small, the raw material solution/catalyst mass ratio and the reaction temperature are low, the purity and yield of methyl 3-hydroxypropionate can be greatly increased, the process is simple, and the course is stable. Thus, the invention can be easily used in the large-scale production of methyl 3-hydroxypropionate.
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