Diffusion tensor imaging and disability progression in multiple sclerosis : a 4-year follow-up study

Objectives Diffusion tensor imaging (DTI) is sensitive technique to detect widespread changes in water diffusivity in the normal‐appearing white matter (NAWM) that appears unaffected in conventional magnetic resonance imaging. We aimed to investigate the prognostic value and stability of DTI indices in the NAWM of the brain in an assessment of disability progression in patients with a relapsing‐onset multiple sclerosis (MS).