Supramolecular Assembly of Toll-like Receptor 7/8 Agonist into Multimeric Water-Soluble Constructs Enables Superior Immune Stimulation In Vitro and In Vivo

Resiquimod or R848 (RSQD) is a Toll-like receptor (TLR) 7/8 agonist that shows promise as vaccine adjuvant due to its potential to promote highly desirable cellular immunity. The development of thi...