Correlation analysis of prostate cancer incidence and mortality worldwide, in Europe and in Bulgaria

An in-depth overview of the prostate cancer incidence and mortality rates, based on the geographical location, race and ethnicity on global, European and national scales, shows ambiguous, incompatible and sometimes unreliable data. The aim of this study is to analyze the incidence and mortality rates worldwide, in Europe and in Bulgaria. Data from global databases (Globocan) and the National Statistical Institute of Bulgaria are used. The global incidence and mortality rates of prostate cancer correlate with age. The median age at the time of the diagnosis is 66 years. International trends in prostate cancer incidence and mortality have varied significantly in recent years, closely related to the PSA screening used for early detection of the disease, mostly in the Western countries. Data sources show a discrepancy in the incidence and mortality rates in men of different races and geographical origins. This confirms the role of genetic factors in the pathogenesis of prostate cancer. Discrepancies between men of the same race and ethnicity, living in different countries, suggests that other factors such as diet and socioeconomic status, different methods of diagnosis and treatment are also important. The highest incidence rate is expected in the developed countries and the highest mortality rate in the developing countries.