Evaluation and comparison of antibacterial activity of leaves, seeds and fruits extract of momordica charantia

Momordica charantia is a well known plant in Asia including India which posses wide range of pharmacological activities. These drug have been used in India as folk remedy in the form of decoctions and infusions to treat bacterial infections and also claimed to be an effective against variety of skin conditions like psoriasis, acne, wounds etc. The present investigation is carried out to study and compare antibacterial activity of different parts of Momordica charantia extracts with different solvents on four microorganisms by disk diffusion method. Methanolic, ethanolic, petroleum ether and aqueous extract of leaves, seeds and fruits of the plant were evaluated for antibacterial activity using the disk diffusion method on four microorganisms (Staphylococcus aures, Pseudomonas aeruginosa, Escherichia coli, and Salmonella typhi). Zone of inhibition was calculated. Results indicate that the different concentrations of various extracts under study exhibit antibacterial activity and among the various extracts, fruit extracts have shown better activity as compared to other parts of extracts. Among the