Disease therapeutic composition comprising a combination of microflora derived bioactive molecule

Composition comprising microflora derived bioactive molecules mammal is provided herein. The composition, if accompanied by colonic delivery system is administered orally, the disease is especially useful in the prevention and treatment of inflammatory diseases, autoimmune diseases and infectious diseases. The composition comprises a combination of small molecules and bacterial antigens formulated in colonic delivery system. The use of the composition: immune tolerance induction; brought and inflammation, any or all of the autoimmune response or palliation of the disease state of being caused by infectious agents; enhanced integrity of the intestinal mucosal barrier; reducing inflammation It is. .FIELD 4-1