Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium

Cedrik M. Britten,Sylvia Janetzki,Leah Ben Porat,Timothy M. Clay,Michael Kalos,Holden T. Maecker,Kunle Odunsi,Michael Pride,Lloyd J. Old,Axel Hoos,Pedro Romero

Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium

2009

Cedrik M. Britten
Sylvia Janetzki
Leah Ben Porat
Timothy M. Clay
Michael Kalos
Holden T. Maecker
Kunle Odunsi
Michael Pride
Lloyd J. Old
Axel Hoos
Pedro Romero

Purpose The Cancer Vaccine Consortium of the Cancer Research Institute (CVC-CRI) conducted a multicenter HLA-peptide multimer proficiency panel (MPP) with a group of 27 laboratories to assess the performance of the assay.

Keywords:

Protein multimerization
Virology
Cancer
Immunology
Cancer vaccine
Harmonization
Medicine
Human leukocyte antigen
tumor immunity

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