Relations between genetic background and intracardiac scars characteristics in patients with arrhythmogenic right ventricular cardiomyopathy

Introduction Relations between scars characteristics and genetic background in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) has not been investigated so far. Objective To investigate if genetic background change the scars characteristics in ARVC. Method 66 patients with ARVC (24 with culprit mutation) having undergone endocardial mapping have been retrospectively included. Every patient had a diagnosis of ARVC according to the task force criteria. Localisations, surfaces and perimeters of low votage areas ( Results Mutated patients more often had altered right ventricular ejection fraction ( Conclusion In our ARVC population, culprit mutations increase size and number of intracardiac scars and degree of biventricular involvment, and localize scars in infero-lateral areas compared to patients without mutation.