Comparative plasma disposition and anticoagulant activities of racemic phenprocoumon and its metabolites in rats

Jan X. De Vries,Michael Simon,Uwe Völker,Ingeborg Walter-Sack,E. Weber,K. Stegmeier

Comparative plasma disposition and anticoagulant activities of racemic phenprocoumon and its metabolites in rats

1993

Jan X. De Vries
Michael Simon
Uwe Völker
Ingeborg Walter-Sack
E. Weber
K. Stegmeier

The anticoagulant phenprocoumon (PH) and its metabolites 6-hydroxy-, 7-hydroxy- and 4′hydroxy-phenprocoumon (6-OH-PH, 7-OH-PH and 4′-OH-PH, respectively) were separately administrated intravenously as

Keywords:

Phenprocoumone
Prothrombin time
Anticoagulant
Animal model
Phenprocoumon
Metabolite
Anticoagulant activity
Pharmacology
Disposition
Chemistry

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