Pan-proteomics: Technologies, applications, and challenges

Abstract Proteomic analysis is a discipline that has been utilized to understate the global protein dynamic in one cell through quantitative and qualitative studies. Due to all these technological advances, the proteomic study has contributed to broaden our knowledge about drug discovery, microbial meta-proteomics in distinct environmental, plant proteomic, host-pathogen interaction, human or animal health. More recently, proteomic studies have been utilized in pan-proteomic studies. This strategy aim compares all proteins of several organisms with genetic variation, enabling through qualitative or/and quantitative strategies to identify the entire proteome and promote information attributions about the biology of organisms within a given specie. Here in this chapter, we provide information and discussion about the contribution of the pan-proteomic study into different areas of knowledge such as microbiology, botany and zoology to elucidate important factors related to basic life processes. In addition, we also discuss about proteomics technologies and bioinformatics strategies developed to increase the proteomic power.