The Prevalence of uterine septum in polycystic ovarian syndrome (PCOS), a series of 49 cases
2020
Objective
To estimate the prevalence of uterine septum in patients with polycystic ovarian syndrome(PCOS) that
were investigated for infertility after failure to achieve pregnancy with ovulation induction in a highincidence
area, such as Middle East.
Design
A prospective observational study
Methods
A 49 patients from a total of 172 patients seeking fertility advice at a specialised fertility clinic in
Amman, Jordan, during the period of September 2017 to July 2018 with confirmed polycystic ovarian
syndrome were screened for the presence of congenital uterine anomalies by a
hysterosalpingogram(HSG). The anomalies were classified according to the American Fertility Society
classification. If an anomaly was suspected a diagnostic laparoscopy and hysteroscopy were performed
to confirm the diagnosis.
Results
15 patients (31%) of the 49 patients with confirmed diagnosis of polycystic ovarian syndrome were
confirmed to have uterine anomalies; 11 patients had a uterine septum, three patients had an arcuate
uterus and one patient had a bicornuate uterus.
Conclusion
There is association between PCOS and uterine septum. This study hopes to enlighten infertility
clinicians about the presence of uterine factor in PCOS patients (31%) and the need to screen for this
congenital anomaly at their first consultation before embarking on the time-consuming and costly
process of ovulation induction.
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