Hétérochromie Irienne Congénitale Bilatérale : A Propos de Trois Cas au CHU-IOTA

RESUME L’heterochromie irienne est un signe frequemment decrit dans le syndrome de Claude Bernard Horner congenital. Dans sa forme isolee congenitale, elle a fait l’objet de peu de publications.  Nous presentons trois cas recus en consultation au CHU-IOTA a Bamako. Nous avons enrole trois enfants de moins de 10 ans sans antecedents pathologiques notables chez qui, nous avons retenu le diagnostic de l’heterochromie irienne bilaterale congenitale et isolee. Dans la revue de la litterature, il apparait que l’heterochromie irienne bilaterale serait hereditaire, de transmission autosomique dominante, ou par mutation genetique spontanee. Anomalie de pigmentation, l’heterochromie irienne congenitale et bilaterale est rare a Bamako. ABSTRACT Iris heterochromia is a common occurrence in congenital Claude Bernard Horner syndrome. However, there are few data on the isolated form of iris heterochromia congenital. In this paper, we report three cases that we received in consultation at CHU-IOTA (Bamako). These were three children, aged less than 10 years, and with no significant medical history. A clinical diagnosis of bilateral congenital isolated iris heterochromia was retained. The literature review suggests that iris heterochromia may be hereditary, autosomal dominant transmission, or by spontaneous genetic mutation. Congenital bilateral iris heterochromia is pigmentation disorder that is uncommon in our practice.