Device for transdermal administration of active principles.

Patch two layers for dermal or transdermal administration of active principles consisting of: a) a first layer having a homogeneous composition and consists of - at least one active principle, - forming agent water soluble film selected from the group It is consisting of carboxymethylcellulose, chitosan, aqueous dispersions of acrylic and methacrylic polymers and poly (vinyl alcohol), - a hydrophilic adhesive polymer chosen from the group is consisting of polyvinylpyrrolidone, tragacanth gum, gum arabic, karaya gum, xanthan gum, pectin and adhesives polyaminomethacrylate, - at least one substance which acts as absorption promoter and / or humectant and / or plasticizer selected from the group consisting of glycerine, ethyl alcohol, propylene glycol, polyethylene glycol of molecular weight between 400 and 6000, sorbitol, phospholipids , terpenes, soy lecithin, phosphatidylcholine, cholesterol, cyclodextrin, miristat or isopropyl, oleic acid, polysorbate 80 and diethylene glycol monoethyl ether, said first layer (a) a residual water content below 20%; b) a second attached permanently to the first shape and having a water vapor permeability of water of less than 500 g / m2 in 24 hours, provided that layer: when said adhesive in said layer (a) is polyaminomethacrylate and is copolymer butyl methacrylate / methacrylate (2-dimethylaminoethyl) / methyl methacrylate in which the ratio between the monomers is 1: 2: 1, said film-forming agent in water soluble must be different from carboxymethylcellulose.