Chromatin Structure and Protein-DNA Interactions in the 5′-Flanking Region of the Chicken Lysozyme Gene

The exact mechanisms which ensure that a eukaryotic gene is expressed at a specific time in a specific cell are presently unknown. It is, however, generally assumed that the structural organization of chromatin determines the state of differentiation and activity of eukaryotic genes. Our work is aimed at understanding the molecular details of the processes which prepare genes to be differentially and coordinately expressed.