Características clínicas y paraclínicas de pacientes pediátricos con tiroiditis autoinmune en una institución especializada de Cali, Colombia
2020
Autoimmune thyroiditis or Hashimoto´s thyroiditis (HT) is the main cause of acquired
hypothyroidism in iodine-sufficient regions. It is associated with other autoimmune diseases and thyroid
cancer. The goal of this study is to expose clinical manifestations and laboratory findings identified in HT
patients that attended the endocrinology service in a pediatric specialized center in the city of Cali, Colombia.
This is a transversal (cross-sectional) observational retrospective study. Medical records of 91 were
examined, 45 patients fulfilled selection criteria and entered the study. The average age at the time of
diagnosis was 11.5 years old, with a female predominance (75.6%). Hypothyroidism was seen in 44.5% and
hyperthyroidism in 42.2% of the patients. Goiter was the main clinical manifestation found (64.4%), with
anti-peroxidase antibodies being positive in 95.6%. Two patients presented concomitant autoimmune
disease. HT is more common in puberal age females, it can generate permanent hypothyroidism and be
associated with autoimmune diseases. Prompt diagnosis and follow up is important to prevent associated
complications.
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