Trends in the Incidence of In-Hospital mortality, Cardiogenic Shock and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005-2014)

ABSTRACT Background Myocarditis may be associated with hemodynamic instability and portends a poor prognosis when associated with cardiogenic shock (CS). There are limited data available on the incidence of in-hospital mortality, CS, and utilization of mechanical circulatory support (MCS) devices in these patients. Methods We queried the 2005–2014 National Inpatient Sample databases to identify all patients aged >18 years with myocarditis in the United States. Results The number of reported cases of myocarditis per 1 million gradually increased from 95 in 2005 to 144 in 2014 ( P for trend P for trend P P Conclusion Although the incidence of myocarditis has increased in the last decade, the in-hospital mortality has remained the same despite increases in the incidence of CS, possibly reflecting the benefits of increased usage of advanced MCS devices. We noted that increasing age, presence of multiple comorbidities and CS were associated with an increase in in-patient mortality.