Analysis the Relationship beween Viremia and the Serum Marker Models of Hepatitis B with both HBsAg and HBsAb Positive

2010 
Objective To analyze of HBV marker model with both HBsAg and HBsAb positive in the sea of patients with Hepatitis B virus infection and the relationship with HBV DNA.Methods To test the serum HBV markers of the patients by chemiluminescent microparticle immunoassay(CMIA),to choose the samples with both HbsAg and HBsAb positive among them.And to test HBV DNA quantitative by fluorescence quantitative polymerase chain reaction(FQ-PCR).Results Among the 37 cases samples with both HBsAg and HBsAb positive,there were three HBV models:(1)HBsAg、HBsAb、HBeAb、HBcAb positive,the positive rate was 46%,HBV DNA positive rate was 22%;(2)HBsAg、HBsAb、HBeAb、HBcAb positive,the positive rate was 30%,HBV DNA positive rate was 30%;(3)HBsAg、HBsAb、HBeAb、HBcAb positive,the positive rate was 24%,HBV DNA positive rate was 5%;totally there were 21 cases of positive detection of serum HBV DNA,the positive rate was 57%.Conclusion It doesn't represent the disease really recovery that Hepatitis B patients with both HBsAg and HBsAb positive,some patients still come down with viremia,for it should be pay more attention.
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