Carcinoma ex-pleomorphic adenoma of submandibular salivary gland: A case report and review of literature

Pleomorphic adenoma (PA) is the most common benign neoplasm affecting the major salivary glands. It is more common in parotid gland and sometimes occurs in submandibular and other minor salivary glands. Carcinoma ex-pleomorphic adenoma (CXPA) is the malignant transformation of a primary or recurrent PA. Here, we report a case of CXPA of submandibular salivary gland with metastasis in the cervical lymph nodes. He was treated with excision of the mass with radical neck dissection, followed by adjuvant radiotherapy.