N-(2-pyrimidine oxygen based) benzyl hetercyclic compounds, preparation method and uses thereof

2008 
The present invention relates to an N-(2-pyrimidinyloxy) phenmethyl heterocyclic compound. The compound has a general structural formula as shown below, wherein, D or E is hydrogen, halogen, hydroxyl, C1-C4 alkoxyl or C1-C4 halogenating alkoxyl; X is hydrogen, halogen, nitryl, C1-C8 alkyl, C1-C8 halogenating alkyl or C1-C8 alkoxyl; R is hydrogen, halogen, nitryl, cyano, carboxyl, ester group, sulphonyl, C1-C8 alkoxy amido, C1-C8 alkylogen amino, C1 - C8 halogenating alkylogen amino, C1-C8 halogenating alkyl sulfanilamide, C1-C8 alkyloxyacyl, C1-C8 alkyl, C1-C8 halogenating alkyl, benzyl, bezno or heterocyclic radical, C1-C8 alkoxyl, phenoxy or heterocyclic epoxy radical; and the Figure shows conjugate connected through N-N bonds or non-conjugate five-membered heterocycle or six-membered heterocycle.
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