Outcome of interventions in elderly persons classified according to the Fried frailty phenotype: an integrative review

Abstract Objective: To analyze the interventions carried out with elderly persons classified according to the Fried frailty phenotype criteria and the outcomes obtained. Method: The PubMed, Embase, Scopus, CINAHL, PEDro, SciELO, BVS and Web of Science portals were used, and a manual search was applied to identify the interventions implemented in elderly persons aged over 60 years, which were able to modify the scores of the frailty phenotype criteria and other outcomes. Results: The final sample totaled 14 randomized clinical trials published between 2001 and 2018. The combined interventions of exercise, orientation and nutritional supplementation with or without cognitive training presented better outcomes for the frailty criteria and other clinical outcomes in pre-frail and frail elderly persons living in the community and in long-term care facilities. Conclusion: The implementation of combined interventions sustains frailty as a reversible and multifactorial syndrome.