[3H]R75231; A New Radiolabelled Nucleoside Transporter Probe Related to Mioflazine and Lidoflazine
1991
Abstract The transport of nucleosides and analogues across the plasma membrane of animal cells is mediated by nucleoside-specific transport proteins, by means of facilitated diffusion. Development of highly potent tritiated transport inhibitors allowed ligand binding studies, performed at various tissues. [3H]Nitrobenzylthioinosine ([3HINBI) and [3H]dipyridamole are used in this respect, yielding a wealth of information about the molecular characteristics of these proteins (1,2).
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