Blood Anticoagulation Activity of Polysaccharides from Actinopyga mauritiana

Kunming mice and New Zealand rabbits were feeding with different dosage of Actinopyga mauritiana (AMP) by injection. Then the bleeding time and clotting time (CT) of mice were determined by cutting off their tails. The CT of the venous blood of New Zealand rabbit ear was also detected. Results showed that AMP had high blood anticoagulation activity, which cloud significantly prolong the CT.