ВЛИЯНИЕ ВИЧ-ИНФЕКЦИИ НА ДЕМОГРАФИЧЕСКУЮ СИТУАЦИЮ В РОССИИ

Incidence of combination of tuberculosis and HIV-infection increased by 75.4% since 2009 till 2016, prevalence at the end of the year increased by 85,2%. Among dispensary registered people infected with HIV proportion and amount of patients with late stages increases annually. These patients mainly suffers from tuberculosis which provides unfavorable prognosis of epidemiological situation with tuberculosis in Russia after 2020 in case of keeping trend of increasing prevalence of tuberculosis and HIV co-infection. Incidence of tuberculosis among HIV-infected permanent population registered in 2016 is 50 times higher than average for HIV negative Russian population. Infection rates of tuberculosis among HIV-infected patients are highly influenced by overall regional epidemiological situation with tuberculosis, incidence rate of tuberculosis, incidence rate of mycobacterium tuberculosis infection. Medium age of HIV antibodies revealing in 2016 in Russia was 35.3 years including 35.7 years for men and 34.7 years for women. Medium of patients died of HIV-infection was 37.5 years, including 37.9 years for men and 36.6 for women. Because of HIV related mortality 606 552 years of life were not lived. HIV infected women live less than man despite medium data of life duration (generally in Russia women live 10 years longer than men). In Sverdlovsk region since 2010 till 2016 cases of HIV-infection were revealing 5.1 years later; patients died from HIV 4.7 years later, from other reasons 5.0 years later. Life duration from registration of HIV-infection till HIV-related death in 2016 was 6.5 years; till death not related to HIV was 6,4 years. Among known cases of HIV-related death this parameter was 5,9 years and it differs between patients who don’t receive ART - 4.6 years and patients who receive ART and have undetectable viral load - 7.5 years. Between died patients only 7.2% were getting ART and having undetectable viral load. Among patients who died from HIV-infection as older patients were at the time of revealing HIV as more frequent CD4 count less than 200 cells/ml was detected. Time from HIV diagnosis till establishing of diagnosis HIV-infection+ tuberculosis in 2016 was 5.4 years; medium CD4 count before establishing of diagnosis «tuberculosis» among HIV-infected patients was 225.7 cells/ml; mycobacterial infection dominates in structure of HIV-related death. At the same time prevalence of this reason of death started to decrease (2012 - 43.1%; 2016 - 38.7%).