Principles for optimizing chromatographic separation by type of functionality in the critical region as illustrated by hydroxyl-containing oligobutadienes

Possible variants for optimizing the process of chromatographic separation by functionality in critical conditions (using hydroxyl-containing oligobutadienes) including modification of the immobile phase and the functional groups of the oligomer and regulation of the specific interactions of the functional groups in the mobile phase and temperature are analysed. Conditions are selected permitting analysis of the distribution by types offunctionality of telechelate oligobutadienes in critical conditions.