[Risk of the prolapse "de novo" in primary unaffected compartment by using the syntethic mesh in the surgery treatment of the pelvic organe prolapse].

OBJECTIVE: The aim of this retrospective trial was to evaluate the risk of the prolapse "de novo" in primary unaffected compartment by using the syntethic mesh. DESIGN: Rerospective multicentric trial. SETTING: 2nd department of Gynaecology and Obstetrics, Medical Faculty of Safarik's University and L. Pasteur Hospital, Kosice and Gynaecology department, Gynpor, s.r.o., Sliac, Slovakia. POPULATION AND METHODS: One hundred and eleven women with stage > or = 2 prolapse according to the Pelvic Organe Prolapse - Quantification (POP-Q) system was enrolled into the study. In group MESH A (anterior compartment) was 86 (17x Prolift Anterior; 69x Prolift Anterior like MESH and group MESH P (posterior compartment) was 25 (9x Prolift Posterior; 16x Prolift posterior like MESH) of enrolled women. The primary outcome was the risk of POP > or = 2 "de novo" prolapse in primary unaffected compartment at 12 months follow-up. The second was the efficacy of the treatment by using synhetic mesh. Third was: Did uterus sparing operation increase the risk of reccurance of the prolapse. Complications was also reported. RESULTS: For subject attendigs the 12-month follow-up, the risk of "de novo" prolapse in MESH A group was 20.9% (17/86) compared with only 16% (4/25) in the MESH P group and was not significantly different (p<0.13). The efficacy was 91.6% in the MESH A group and 84% in the MESH P group and was not significantly different. Uterus sparing operation did not increase the risk the prolapse,,de novo" in primary unaffected compartment. Vaginal mesh exposure occured in 14.4%. CONCLUSION: Vaginal repair by using MESH is effective in the treatment of the pelvic organe prolapse, but is posible to provoke the development of prolapse in primary unaffected compartment.