Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Anzhelika Vorobyeva,Alexey Sсhulga,Elena Konovalova,Rezan Güler,Bogdan Mitran,Javad Garousi,Sara S. Rinne,John Löfblom,Anna Orlova,S. M. Deyev,Vladimir Tolmachev

Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

2019

Anzhelika Vorobyeva
Alexey Sсhulga
Elena Konovalova
Rezan Güler
Bogdan Mitran
Javad Garousi
Sara S. Rinne
John Löfblom
Anna Orlova
S. M. Deyev
Vladimir Tolmachev

Evaluation of human epidermal growth factor receptor 2 (HER2) expression levels in breast and gastroesophageal cancer is used for the stratification of patients for HER2-targeting therapies. The us ...

Keywords:

Molecular medicine
Cancer research
Cell
Cell cycle
Gene
Cancer
Molecular imaging
Oncogene
DARPin
Biology
Ankyrin repeat
Positron emission tomography
Scaffold protein
Biodistribution
Single-photon emission computed tomography

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