Use of Adalimumab in a Patient with Juvenile Idiopathic Arthritis Refractory to Etanercept: a Case Report and Literature Review

In this report, we present a child patient diagnosed with juvenile idiopathic arthritis (JIA) refractory to disease-modifying anti-rheumatic drugs (DMARDs), Methylprednisolone pulse therapy, and the TNF-α-inhibitor etanercept, with a significant improvement in hematologic abnormalities after the introduction of adalimumab.