Биосовместимость материалов для эписклерального пломбирования (экспериментально-морфологическое исследование)

A morphological study of enucleated rabbit eyes was performed to evaluate the biocompatibility of allogenic connective tissue and silicone sponge. The morphologic analysis was performed at different terms after episcleral buckling. It was found that the silicone sponge promoted a moderate to severe inflammatory and mild allergic local tissue reactions. These lead to the implant encapsulation, scar formation, and significant scleral thinning at the buckling site. The allogenic biomaterial evoked a mild inflammatory local tissue reaction, slowly resorbed, and was replaced by dense connective tissue. The allogenic buckle has several advantages over the silicone sponge, and could be recommended for a wide clinical use in episcleral retinal detachment procedures.