Plasma and Intracellular Pharmacokinetic (PK) Analysis of Fludarabine in Pediatric Allogeneic Hematopoietic Cell Transplant (alloHCT) Recipients

2014 
s / Biol Blood Marrow Transplant 20 (2014) S27eS44 S30 PT-Cy. We show it is a safe regimen, with high engraftment rates, encouraging survival rates and very low grade III-IV aGvHD and extensive cGVHD rates despite relatively high T cells doses. The results from this relatively small number of mostly high-risk patients are encouraging and form basis for testing it in a larger cohort of patients. TNC <8 10 cells/ kg TNC 8 10 cells/ kg P CD34+ <4 10
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