A New Approach to Axially Chiral Biaryls via the Atrop-Diastereoselective Formation of Medium-Sized Lactone Bridge
2016
Biphenyl-2,6-diols, substituted at the C2′ position with alkanoic acid side chain containing a stereogenic center, underwent the highly atrop-stereoselective nine-membered lactone formation with differentiation of the diastereotopic hydroxy groups.
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