MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases.

Ying Meng,Raymond M. Reilly,Rossanna C. Pezo,Maureen E. Trudeau,Arjun Sahgal,Amit Singnurkar,James Perry,Sten Myrehaug,Christopher B. Pople,Benjamin Davidson,Maheleth Llinas,Chinthaka Hyen,Yuexi Huang,Clement Hamani,Suganth Suppiah,Kullervo Hynynen,Nir Lipsman

MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases.

2021

Ying Meng
Raymond M. Reilly
Rossanna C. Pezo
Maureen E. Trudeau
Arjun Sahgal
Amit Singnurkar
James Perry
Sten Myrehaug
Christopher B. Pople
Benjamin Davidson
Maheleth Llinas
Chinthaka Hyen
Yuexi Huang
Clement Hamani
Suganth Suppiah
Kullervo Hynynen
Nir Lipsman

The blood-brain barrier (BBB) is an important factor limiting the effectiveness of central nervous system (CNS) therapeutics. MR-guided focused ultrasound (MRgFUS) is a noninvasive, spatially preci...

Keywords:

Central nervous system
Trastuzumab
Limiting
Medicine
Radiology
mri guided
focused ultrasound

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