Prognostic significance of regional edema and quantitative assessment of late gadolinium enhancement in patients with acute myocarditis

Background Standard diagnostic CMR criteria for acute myocarditis have been proposed (ie Lake Louise criteria) based upon the any 2 of 3 approach which includes the presence of myocardial edema (T2), hyperemia/capillary leakage (early Gd enhancement: EGE) as well as fibrosis (late enhancement: LGE). However, there is a lack of prognostic data using these criteria. The aim of this study was to evaluate the diagnostic CMR criteria for the prediction of functional outcome in patients with myocarditis.