Cerebral autoregulation in hypertensive patients: A review
2021
Cerebral Autoregulation (AR) consists of a complex mechanism characterized by the
ability of the brain microcirculation to contract and dilate in response to variations in
Blood Pressure (BP), aiming at maintaining a constant Cerebral Blood Flow (CBF).
Vascular changes induced by Systemic Arterial Hypertension (SAH), such as thickening
of the smooth muscle layer and intimal proliferation, result in reduced luminal
diameter and increased cerebrovascular resistance (CVR). Here, the mechanisms of AR
and the repercussions of these histological changes on the microcirculatory capacity
to maintain constant CBF in these patients will be reviewed. The material for this
review was taken mostly from electronic journals. To collect publications, PubMed e
Cochrane database of systematic reviews were used.
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