Characterization of HPMC/PVP polymer blend films using WAXS technique

Hydroxy propyl methyl cellulose (HPMC) and Poly vinyl pyrrolidone (PVP) polymer blend films were prepared and investigated using X-ray line profile analysis method. Here an attempt has been made to study the changes in the crystallite size and lattice strain in HPMC with the increase in concentration of PVP. Decrease in these microcrystalline parameters implies increase in the amorphous nature of the film giving more flexibility, degradability and good miscibility. Micro structural parameters reveals that the blend films have more amorphous nature than virgin HPMC. This further justified by SEM images which indicate better miscibility of the two polymers in the blend matrix.