A REVIEW ON PULMONARY DRUG DELIVERY SYSTEM

Targeting the drug delivery into the lungs has become one of the most important aspects of the systemic or the local drug delivery. The pulmonary tract tends to be considered as very attractive & promising route for the administration of the active substances intended to treat the local pulmonary for e.g., COPD (chronic obstructive pulmonary disease), asthma, microbial infections as well as the systemic diseases for e.g, diabetes. The human respiratory system is complicated organ system these systems consist of two reagions conducting airways & respiratory region. The airway is further divided into many folds such as the nasal cavity, oropharynx, nasopharynx, trachea, larynx, bronchioles & bronchi. The respiratory region consists of respiratory bronchioles, alveolar sac & alveolar ducts. This present review discusses the challenges in pulmonary drug delivery, advantages, different factors affecting pulmonary drug delivery, different pulmonary delivery devices, evaluation of pulmonary drug delivery devices and applications for pulmonary drug delivery system