O Tempo e a Anestesia Obstétrica: da Cosmologia Caótica à Cronobiologia * Time and Obstetric Anesthesia: from Chaotic Cosmology to Chronobiology*

SUMMARY Vale NB, Vale LFB, Cruz JR – Time and Obstetric Anesthesia: FromChaotic Cosmology to Chronobiology. BACKGROUND AND OBJECTIVES: Temporal cycles (dark/light;birth/death; etc.), along with environmental conditions (synchro-nizers), influence labor physiology because of the presence ofendogenous clocks (oscillators) that interact with social diuturnalclues. In this review, the most important cyclic anesthetic-obstetricparameters in parturient care are listed. CONTENTS: Chronobiological analysis of the main events in theobstetric pathophysiology of Mulier sapiens: I) Embryogenesis –risk of teratogenesis; II) From prematurity to post-didacticism: fromeutocic labor to cervical cerclage; III) Night and labor: higherincidence of nocturnal labor (physiological facilitation) and daylightcesarean section (choice of the obstetrician); IV) The moon andlabor – non-conclusive results; V) The night shift in obstetricanesthesia: riskier professional contingency; VI) Phases of ce-sarean section: removal of the fetus: UD stage (uterotomy – delivery)as brief as possible; effective correction of hypotension and valo-rize pre-anesthetic fasting; VII) circadian variation of dystocia: pain;uterine contraction; blood loss; hypertension (HTN); risk of allergyand asthma. In the nocturnal phase, the intensity of contraction andrisk of hemorrhage, allergy, and asthma are greater. On the otherhand, HTN in eclampsia does not show circadian variation; VIII)Obstetric chronopharmacology: local anesthetics, analgesics,hypnotics, general anesthetics, and neuromuscular blockers.Chronoenergy explains the matinal peak of opioid analgesia,vespertine of local anesthetic, and nocturnal of inhalationalanesthetics.