Studies with Brugia pahangi. 18. Anthelmintic effects of stibocaptate.
1978
Stibocaptate ( Astiban , Hoffman - La Roche) killed third stage larvae of Brugia pahangi in vitro at 50 p.p.m. but had no effect on microfilariae at 1 × 10 4 p.p.m. No larvae developed in infected mosquitoes fed 1% stibocaptate in 10% sucrose. It was neither micro-nor macrofilaricidal in neither jirds or cats but did affect embryogenesis.
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