Rh(III)-Catalyzed Hydroarylation of Alkyne MIDA Boronates via C–H Activation of Indole Derivatives

An efficient approach to trans-indolylvinylboronate derivatives has been developed using an Rh-catalyzed hydroarylation of alkyne N-methyliminodiacetic acid boronates via C–H activation. This protocol constitutes a straightforward route for the synthesis of B-containing aza-heterocycles in good yields with excellent functional group tolerance.