Neuroleptic malignant syndrome induced acute renal failure: Is mental retardation an additional risk factor?

Abstract Neuroleptic malignant syndrome is a rare but serious complication of neuroleptic treatment. It is a disorder which is usually characterized by muscle contraction and changes in consciousness, extrapyramidal symptoms, hyperpyrexia and blood pressure irregularities that often depend on the use of conventional antipsychotic drugs. In this case report, we discuss acute renal failure induced by neuroleptic malignant syndrome developing on the basis of chronic kidney disease in a patient with mental retardation. Keywords: Neuroleptic malign syndrome; mental retardation; acute renal failure Ozet Noroleptik malign sendrom, noroleptik tedavinin nadir; ancak, ciddi bir komplikasyonudur. Siklikla klasik antipsikotik ilaclarin kullanimina bagli olarak gelisen ekstrapiramidal semptomlar, hiperpreksi, kan basincinda duzensizlikler, genellikle kaslarda kasilma ve bilincde degisiklikler ile karakterize bir hastaliktir. Bu olgu sunumunda mental gerilik olan bir hastada kronik bobrek hastaligi zemininde gelisen ve noroleptik malign sendromun olusturdugu akut bobrek yetmezligini tartismaktayiz. Anahtar sozcukler: Noroleptik malign sendrom, mental gerilik, akut bobrek yetmezligi