Abstract 15266: Nanoparticle-Mediated Simultaneous Targeting of Mitochondria and Inflammatory Monocytes Attenuates Cerebral Ischemia-Reperfusion Injury in Mice

Arihide Okahara,Tetsuya Matoba,Jun-ichiro Koga,Masaki Fujiwara,Daiki Funamoto,Kaku Nakano,Hiroyuki Tsutsui,Kensuke Egashira

Abstract 15266: Nanoparticle-Mediated Simultaneous Targeting of Mitochondria and Inflammatory Monocytes Attenuates Cerebral Ischemia-Reperfusion Injury in Mice

2017

Arihide Okahara
Tetsuya Matoba
Jun-ichiro Koga
Masaki Fujiwara
Daiki Funamoto
Kaku Nakano
Hiroyuki Tsutsui
Kensuke Egashira

Introduction: The early reperfusion is a principal therapeutic strategy for the treatment of acute cerebral infarction. Opening of mitochondrial permeability transition pore (mPTP), regulated by cy...

Keywords:

Inflammation
Cerebral infarction
MPTP
Internal medicine
Pharmacology
Mitochondrion
Ischemia
Cardiology
Neuroprotection
Reperfusion injury
Mitochondrial permeability transition pore
Medicine
Stroke

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